Multiphoton-Excited Serotonin Photochemistry

Single and multiphoton excited fluorescence from serotonin complexed with Bcyclodextrin

Ovarian Cancer Cell Adhesion/Migration Dynamics on Micro-Structured Laminin Gradients Fabricated by Multiphoton Excited Photochemistry

Haptotaxis, i.e., cell migration in response to adhesive gradients, has been previously implicated in cancer metastasis. A better understanding of cell migration dynamics and their regulation could ultimately lead to new drug targets, especially for cancers with poor prognoses, such as ovarian cancer. Haptotaxis has not been well-studied due to the lack of biomimetic, biocompatible models, wher...

Multiphoton excited coherent random laser in ZnO powders

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Multiphoton-Excited Fluorescence of Silicon-Vacancy Color Centers in Diamond

Silicon-vacancy color centers in nanodiamonds are promising as fluorescent labels for biological applications, with a narrow, nonbleaching emission line at 738 nm. Two-photon excitation of this fluorescence offers the possibility of low-background detection at significant tissue depth with high threedimensional spatial resolution. We measure the two-photon fluorescence cross section of a negati...

Optimizing ultrafast illumination for multiphoton-excited fluorescence imaging

We study the optimal conditions for high throughput two-photon excited fluorescence (2PEF) and three-photon excited fluorescence (3PEF) imaging using femtosecond lasers. We derive relations that allow maximization of the rate of imaging depending on the average power, pulse repetition rate, and noise characteristics of the laser, as well as on the size and structure of the sample. We perform ou...